Kif5b is an essential forward trafficking motor for the Kv1.5 cardiac potassium channel

We have investigated the role of the kinesin I isoform Kif5b in the trafficking of a cardiac voltage-gated potassium channel, Kv1.5. In Kv1.5-expressing HEK293 cells and H9c2 cardiomyoblasts, current densities were increased from control levels of 389 ± 50.0 and 317 ± 50.3 pA pF(−1), respectively, t...

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Autores principales: Zadeh, Alireza Dehghani, Cheng, Yvonne, Xu, Hongjian, Wong, Nathan, Wang, Zhuren, Goonasekara, Charitha, Steele, David F, Fedida, David
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2009
Materias:
Molecular and Cellular
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768013/
https://ncbi.nlm.nih.gov/pubmed/19675065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.178442
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