Adipocyte expression of PU.1 transcription factor causes insulin resistance through upregulation of inflammatory cytokine gene expression and ROS production

We have reported previously that ETS family transcription factor PU.1 is expressed in mature adipocytes of white adipose tissue. PU.1 expression is increased greatly in mouse models of genetic or diet-induced obesity. Here, we show that PU.1 expression is increased only in visceral but not subcutane...

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Autori principali: Lin, Ligen, Pang, Weijun, Chen, Keyun, Wang, Fei, Gengler, Jon, Sun, Yuxiang, Tong, Qiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378156/
https://ncbi.nlm.nih.gov/pubmed/22454293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00462.2011
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