Inhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium

Virulent intracellular pathogens, such as the Salmonella species, engage numerous virulence factors to subvert host defence mechanisms to induce a chronic infection that leads to typhoid or exacerbation of other chronic inflammatory conditions. Here we show the role of the forkhead transcription fac...

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Vydáno v:Nat Commun
Hlavní autoři: Joseph, Julie, Ametepe, Emmanuelle S., Haribabu, Naveen, Agbayani, Gerard, Krishnan, Lakshmi, Blais, Alexandre, Sad, Subash
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023958/
https://ncbi.nlm.nih.gov/pubmed/27599659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12748
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