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Ferritin upregulates hepatic expression of bone morphogenetic protein 6 and hepcidin in mice

Hepcidin is a hepatocellular hormone that inhibits the release of iron from certain cell populations, including enterocytes and reticuloendothelial cells. The regulation of hepcidin (HAMP) gene expression by iron status is mediated in part by the signaling molecule bone morphogenetic protein 6 (BMP6...

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Bibliographic Details
Main Authors: Feng, Qi, Migas, Mary C., Waheed, Abdul, Britton, Robert S., Fleming, Robert E.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378091/
https://ncbi.nlm.nih.gov/pubmed/22517766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00020.2012
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