The OPCML Tumor Suppressor Functions as a Cell Surface Repressor-Adaptor, Negatively Regulating Receptor Tyrosine Kinases in Epithelial Ovarian Cancer

Epithelial ovarian cancer (EOC) is the leading cause of death from gynecologic malignancy and its molecular basis is poorly understood. We previously showed that OPCML was frequently epigenetically inactivated in EOC, with suppressor function in-vitro and in-vivo. Here, we further show the clinical...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: McKie, Arthur B., Vaughan, Sebastian, Zanini, Elisa, Okon, Imoh S., Louis, Louay, de Sousa, Camila, Greene, Mark I., Wang, Qiang, Agarwal, Roshan, Shaposhnikov, Dmitry, Wong, Joshua LC, Gungor, Hatice, Janczar, Szymon, El-Bahrawy, Mona, Lam, Eric W-F, Chayen, Naomi E., Gabra, Hani
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378039/
https://ncbi.nlm.nih.gov/pubmed/22585860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-11-0256
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