WWOX sensitises ovarian cancer cells to paclitaxel via modulation of the ER stress response

There are clear gaps in our understanding of genes and pathways through which cancer cells facilitate survival strategies as they become chemoresistant. Paclitaxel is used in the treatment of many cancers, but development of drug resistance is common. Along with being an antimitotic agent paclitaxel...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Janczar, Szymon, Nautiyal, Jaya, Xiao, Yi, Curry, Edward, Sun, Mingjun, Zanini, Elisa, Paige, Adam JW, Gabra, Hani
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550887/
https://ncbi.nlm.nih.gov/pubmed/28749468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.346
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