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WWOX mRNA expression profile in epithelial ovarian cancer supports the role of WWOX variant 1 as a tumour suppressor, although the role of variant 4 remains unclear

WWOX is a candidate tumour suppressor gene that exhibits LOH or homozygous deletion in several tumour types. As well as the predominant full-length transcript (variant 1) there also exist alternatively spliced transcripts found previously only in malignant tissue. It has been suggested that proteins...

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Autori principali: GOURLEY, C., PAIGE, A.J.W., TAYLOR, K.J., SCOTT, D., FRANCIS, N.-J., RUSH, R., ALDAZ, C.M., SMYTH, J.F., GABRA, H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166600/
https://ncbi.nlm.nih.gov/pubmed/15870886
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