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DBIRD integrates alternative mRNA splicing with RNA polymerase II transcript elongation
Alternative mRNA splicing is the main reason vast mammalian proteomic complexity can be achieved with a limited number of genes. Splicing is physically and functionally coupled to transcription, and is greatly affected by the rate of transcript elongation(1,2,3). As the nascent pre-mRNA emerges from...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378035/ https://ncbi.nlm.nih.gov/pubmed/22446626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10925 |
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