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Evidence that Transcript Cleavage Is Essential for RNA Polymerase II Transcription and Cell Viability
During transcript elongation in vitro, backtracking of RNA polymerase II (RNAPII) is a frequent occurrence that can lead to transcriptional arrest. The polymerase active site can cleave the transcript during such backtracking, allowing transcription to resume. Transcript cleavage is either stimulate...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cell Press
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2994637/ https://ncbi.nlm.nih.gov/pubmed/20417599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.02.026 |
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