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Characterization of Human DNA Polymerase Delta and Its Subassemblies Reconstituted by Expression in the Multibac System
Mammalian DNA polymerase δ (Pol δ), a four-subunit enzyme, plays a crucial and versatile role in DNA replication and DNA repair processes. We have reconstituted human Pol δ complexes in insect cells infected with a single baculovirus into which one or more subunits were assembled. This system allowe...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3377666/ https://ncbi.nlm.nih.gov/pubmed/22723953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039156 |
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