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Characterization of Human DNA Polymerase Delta and Its Subassemblies Reconstituted by Expression in the Multibac System

Mammalian DNA polymerase δ (Pol δ), a four-subunit enzyme, plays a crucial and versatile role in DNA replication and DNA repair processes. We have reconstituted human Pol δ complexes in insect cells infected with a single baculovirus into which one or more subunits were assembled. This system allowe...

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מידע ביבליוגרפי
Main Authors: Zhou, Yajing, Meng, Xiao, Zhang, Sufang, Lee, Ernest Y. C., Lee, Marietta Y. W. T.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377666/
https://ncbi.nlm.nih.gov/pubmed/22723953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039156
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