Llwytho...

The p12 subunit of human polymerase delta modulates the rate and fidelity of DNA synthesis

This study examines the role of the p12 subunit in the function of the human DNA polymerase δ (Pol δ) holoenzyme by comparing the kinetics of DNA synthesis and degradation catalyzed by the four subunit complex, the three subunit complex lacking p12, and site directed mutants of each lacking proofrea...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Meng, Xiao, Zhou, Yajing, Lee, Ernest Y. C., Lee, Marietta Y. W. T., Frick, David N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860660/
https://ncbi.nlm.nih.gov/pubmed/20334433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100042b
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