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The p12 subunit of human polymerase delta modulates the rate and fidelity of DNA synthesis
This study examines the role of the p12 subunit in the function of the human DNA polymerase δ (Pol δ) holoenzyme by comparing the kinetics of DNA synthesis and degradation catalyzed by the four subunit complex, the three subunit complex lacking p12, and site directed mutants of each lacking proofrea...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860660/ https://ncbi.nlm.nih.gov/pubmed/20334433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100042b |
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