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Murine but Not Human Basophil Undergoes Cell-Specific Proteolysis of a Major Endoplasmic Reticulum Chaperone

INTRODUCTION: Basophil has been implicated in anti-parasite defense, allergy and in polarizing T(H)2 response. Mouse model has been commonly used to study basophil function although the difference between human and mouse basophils is underappreciated. As an essential chaperone for multiple Toll-like...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Bei, Staron, Matthew, Li, Zihai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377640/
https://ncbi.nlm.nih.gov/pubmed/22724016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039442
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