Physiologically Based Pharmacokinetic (PBPK) Modeling of Metabolic Pathways of Bromochloromethane in Rats

Bromochloromethane (BCM) is a volatile compound and a by-product of disinfection of water by chlorination. Physiologically based pharmacokinetic (PBPK) models are used in risk assessment applications. An updated PBPK model for BCM is generated and applied to hypotheses testing calibrated using vapor...

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Main Authors: Cuello, W. S., Janes, T. A. T., Jessee, J. M., Venecek, M. A., Sawyer, M. E., Eklund, C. R., Evans, M. V.
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2012
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377357/
https://ncbi.nlm.nih.gov/pubmed/22719758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/629781
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