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Development of Physiologically Based Pharmacokinetic Model (PBPK) of BMP2 in Mice
Bone Morphogenetic protein 2 holds great promise for potential applications in the clinic. It is a potent growth factor for the use in the cervical spine surgery (FDA approved 2002) and has been marketed as “Infuse” for treating open tibial shaft fractures (FDA approved 2004). However, its use is li...
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| Publicado no: | Biol Syst Open Access |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254668/ https://ncbi.nlm.nih.gov/pubmed/25485286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2329-6577.1000123 |
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