The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions

Acute and chronic inflammatory disorders are characterized by detrimental cytokine and chemokine expression. Frequently, the chemotactic activity of cytokines depends on a modified N-terminus of the polypeptide. Among those, the N-terminus of monocyte chemoattractant protein 1 (CCL2 and MCP-1) is mo...

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Bibliografiske detaljer
Main Authors: Cynis, Holger, Hoffmann, Torsten, Friedrich, Daniel, Kehlen, Astrid, Gans, Kathrin, Kleinschmidt, Martin, Rahfeld, Jens-Ulrich, Wolf, Raik, Wermann, Michael, Stephan, Anett, Haegele, Monique, Sedlmeier, Reinhard, Graubner, Sigrid, Jagla, Wolfgang, Müller, Anke, Eichentopf, Rico, Heiser, Ulrich, Seifert, Franziska, Quax, Paul H A, de Vries, Margreet R, Hesse, Isabel, Trautwein, Daniela, Wollert, Ulrich, Berg, Sabine, Freyse, Ernst-Joachim, Schilling, Stephan, Demuth, Hans-Ulrich
Format: Artigo
Sprog:Inglês
Udgivet: WILEY-VCH Verlag 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377097/
https://ncbi.nlm.nih.gov/pubmed/21774078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100158
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