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STATing the importance of immune modulation by platinum chemotherapeutics
Platinum-based anticancer drugs enhance the immunostimulatory potential of DCs and decrease the immunosuppressive capacity of tumor cells. This immunomodulatory ability is based on the inhibition of STAT6-mediated expression of co-inhibitory molecule PD-L2 and opens up the possibility of using these...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3376994/ https://ncbi.nlm.nih.gov/pubmed/22720254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.2.18126 |
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