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STATing the importance of immune modulation by platinum chemotherapeutics

Platinum-based anticancer drugs enhance the immunostimulatory potential of DCs and decrease the immunosuppressive capacity of tumor cells. This immunomodulatory ability is based on the inhibition of STAT6-mediated expression of co-inhibitory molecule PD-L2 and opens up the possibility of using these...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hato, Stanleyson V., de Vries, I. Jolanda M., Lesterhuis, W. Joost
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376994/
https://ncbi.nlm.nih.gov/pubmed/22720254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.2.18126
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