STAT Family Protein Expression and Phosphorylation State during moDC Development Is Altered by Platinum-Based Chemotherapeutics

The STAT signaling pathway is important in dendritic cell (DC) development and function. Tumor cells can induce STAT signaling, thereby inhibiting DC maturation and immunostimulatory functions, leading to hampered efficacy of DC-based immunotherapies. Platinum-based chemotherapeutics can inhibit STA...

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Bibliographic Details
Published in:J Immunol Res
Main Authors: de Haas, Nienke, de Koning, Coco, di Blasio, Stefania, Flórez-Grau, Georgina, de Vries, I. Jolanda M., Hato, Stanleyson V.
Format: Artigo
Language:Inglês
Published: Hindawi 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594321/
https://ncbi.nlm.nih.gov/pubmed/31309123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7458238
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