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STAT Family Protein Expression and Phosphorylation State during moDC Development Is Altered by Platinum-Based Chemotherapeutics

The STAT signaling pathway is important in dendritic cell (DC) development and function. Tumor cells can induce STAT signaling, thereby inhibiting DC maturation and immunostimulatory functions, leading to hampered efficacy of DC-based immunotherapies. Platinum-based chemotherapeutics can inhibit STA...

詳細記述

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書誌詳細
出版年:J Immunol Res
主要な著者: de Haas, Nienke, de Koning, Coco, di Blasio, Stefania, Flórez-Grau, Georgina, de Vries, I. Jolanda M., Hato, Stanleyson V.
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594321/
https://ncbi.nlm.nih.gov/pubmed/31309123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7458238
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