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FOXO3: A master switch for regulating tolerance and immunity in dendritic cells
Recent findings demonstrate that dendritic cells in prostate tumors induce immune tolerance in tumor antigen-specific CD8(+) T cells. We propose that DC tolerogenicity can be regulated by expression of Foxo3; silencing Foxo3 expression enhances anti-tumor immune responses and renders FOXO3 a potenti...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Landes Bioscience
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3376981/ https://ncbi.nlm.nih.gov/pubmed/22720261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.2.18241 |
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