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Foxo3 controls the magnitude of T cell immune responses by modulating dendritic cell function
Foxo transcription factors regulate cell cycle progression, survival, and DNA repair pathways. Here, we demonstrate that a deficiency in Foxo3 resulted in increased expansion of T cell populations after viral infection. This exaggerated expansion was not T cell intrinsic. Rather, it was caused by th...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712214/ https://ncbi.nlm.nih.gov/pubmed/19363483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1729 |
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