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Foxo transcription factors control regulatory T cell development and function

Foxo transcription factors integrate extrinsic signals to regulate cell division, differentiation and survival, and specific functions of lymphoid and myeloid cells. Here we showed the absence of Foxo1 severely curtailed the development of Foxp3(+) regulatory T (Treg) cells, and those that developed...

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Hlavní autoři: Kerdiles, Yann M., Stone, Erica L., Beisner, Daniel L., McGargill, Maureen A., Ch'en, Irene L., Stockmann, Christian, Katayama, Carol D., Hedrick, Stephen M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034255/
https://ncbi.nlm.nih.gov/pubmed/21167754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.12.002
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