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Immunity to Murine Prostatic Tumors: Continuous Provision of T Cell Help Prevents CD8 T Cell Tolerance and Activates Tumor-Infiltrating Dendritic Cells

We previously reported that tumor-specific CD8(+) T cells (TcR-I) become tolerant in the TRansgenic Adenocarcinoma of the Mouse Prostate (TRAMP) model. In this study, we demonstrate that CD4(+) TcR transgenic (TcR-II) T cells transferred into TRAMP mice became activated in lymph nodes (LNs), traffic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shafer-Weaver, Kimberly A., Watkins, Stephanie K., Anderson, Michael J., Draper, Lauren J., Malyguine, Anatoli, Alvord, W. Gregory, Greenberg, Norman M., Hurwitz, Arthur A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732120/
https://ncbi.nlm.nih.gov/pubmed/19622771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4516
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