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Immunity to Murine Prostatic Tumors: Continuous Provision of T Cell Help Prevents CD8 T Cell Tolerance and Activates Tumor-Infiltrating Dendritic Cells
We previously reported that tumor-specific CD8(+) T cells (TcR-I) become tolerant in the TRansgenic Adenocarcinoma of the Mouse Prostate (TRAMP) model. In this study, we demonstrate that CD4(+) TcR transgenic (TcR-II) T cells transferred into TRAMP mice became activated in lymph nodes (LNs), traffic...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2009
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732120/ https://ncbi.nlm.nih.gov/pubmed/19622771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4516 |
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