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Metabolite Kinetics in C6 Rat Glioma Model Using MRSI of Hyperpolarized [1-(13)C]Pyruvate

In addition to an increased lactate-to-pyruvate ratio, altered metabolism of a malignant glioma can be further characterized by its kinetics. Spatially resolved dynamic data of pyruvate and lactate from C6-implanted female Sprague-Dawley rat brain were acquired using a spiral chemical shift imaging...

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Main Authors: Park, Jae Mo, Josan, Sonal, Jang, Taichang, Merchant, Milton, Yen, Yi-Fen, Hurd, Ralph E., Recht, Lawrence, Spielman, Daniel M., Mayer, Dirk
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376665/
https://ncbi.nlm.nih.gov/pubmed/22334279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.24181
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