Quantitative Nano-Scale Analysis of IgE-FcεRI Clustering and Coupling to Early Signaling Proteins

Antigen-mediated crosslinking of IgE bound to its receptor, FcεRI, initiates a transmembrane signaling cascade that results in mast cell activation in the allergic response. Using immunogold labeling of intact RBL mast cells and scanning electron microscopy (SEM), we visualize molecular reorganizati...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Veatch, Sarah L., Chiang, Ethan N., Sengupta, Prabuddha, Holowka, David A., Baird, Barbara A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376227/
https://ncbi.nlm.nih.gov/pubmed/22397623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp300197p
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