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Functional nanoscale coupling of Lyn kinase with IgE-FcεRI is restricted by the actin cytoskeleton in early antigen-stimulated signaling

The allergic response is initiated on the plasma membrane of mast cells by phosphorylation of the receptor for immunoglobulin E (IgE), FcεRI, by Lyn kinase after IgE-FcεRI complexes are cross-linked by multivalent antigen. Signal transduction requires reorganization of receptors and membrane signali...

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Bibliografski detalji
Izdano u:Mol Biol Cell
Glavni autori: Shelby, Sarah A., Veatch, Sarah L., Holowka, David A., Baird, Barbara A.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221596/
https://ncbi.nlm.nih.gov/pubmed/27682583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-06-0425
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