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Roles for SH2 and SH3 Domains in Lyn Kinase Association with Activated FcεRI in RBL Mast Cells Revealed by Patterned Surface Analysis
In mast cells, antigen-mediated cross-linking of IgE bound to its high affinity surface receptor, FcεRI, initiates a signaling cascade that culminates in degranulation and release of allergic mediators. Antigen-patterned surfaces, in which the antigen is deposited in micron-sized features on a silic...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2767321/ https://ncbi.nlm.nih.gov/pubmed/19427382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2009.04.012 |
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