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Arp2/3 complex is required for actin polymerization during platelet shape change

Platelets undergo a series of actin-dependent morphologic changes when activated by thrombin receptor activating peptide (TRAP) or when spreading on glass. Polymerization of actin results in the sequential formation of filopodia, lamellipodia, and stress fibers, but the molecular mechanisms regulati...

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Bibliographic Details
Main Authors: Li, Zhi, Kim, Eric S., Bearer, Elaine L.
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376088/
https://ncbi.nlm.nih.gov/pubmed/12036877
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