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Arp2/3 complex is required for actin polymerization during platelet shape change

Platelets undergo a series of actin-dependent morphologic changes when activated by thrombin receptor activating peptide (TRAP) or when spreading on glass. Polymerization of actin results in the sequential formation of filopodia, lamellipodia, and stress fibers, but the molecular mechanisms regulati...

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Autors principals: Li, Zhi, Kim, Eric S., Bearer, Elaine L.
Format: Artigo
Idioma:Inglês
Publicat: 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376088/
https://ncbi.nlm.nih.gov/pubmed/12036877
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