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Synthetic Triterpenoids Target the Arp2/3 Complex and Inhibit Branched Actin Polymerization
Synthetic triterpenoids are anti-tumor agents that affect numerous cellular functions including apoptosis and growth inhibition. Here, we used mass spectrometric and protein array approaches and uncovered that triterpenoids associate with proteins of the actin cytoskeleton, including actin-related p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2934661/ https://ncbi.nlm.nih.gov/pubmed/20566646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.103036 |
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