Nuclear importin α and its physiological importance

Importin α is recognized as a classical nuclear localization signal (cNLS) receptor which mediates nucleocytoplasmic transport. However, it rapidly accumulates in the nucleus in response to cellular stresses, including oxidative stress, causing a blockade of the classical nuclear import pathway. We...

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Bibliographic Details
Main Authors: Miyamoto, Yoichi, Loveland, Kate L., Yoneda, Yoshihiro
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376070/
https://ncbi.nlm.nih.gov/pubmed/22808339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.19194
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