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Nuclear retention of importin α coordinates cell fate through changes in gene expression
Various cellular stresses including oxidative stress induce a collapse of the Ran gradient, which causes accumulation of importin α in the nucleus and a subsequent block of nuclear protein import. However, it is unknown whether accumulated importin α performs roles in the nucleus after its migration...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252573/ https://ncbi.nlm.nih.gov/pubmed/21964068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.360 |
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