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Investigation of reactions postulated to occur during inhibition of ribonucleotide reductases by 2′-azido-2′-deoxynucleotides

Model 3′-azido-3′-deoxynucleosides with thiol or vicinal dithiol substituents at C2′ or C5′ were synthesized to study reactions postulated to occur during inhibition of ribonucleotide reductases by 2′-azido-2′-deoxynucleotides. Esterification of 5′-(tert-butyldiphenylsilyl)-3′-azido-3′-deoxyadenosin...

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Autors principals: Dang, Thao P., Sobczak, Adam J., Mebel, Alexander M., Chatgilialoglu, Chryssostomos, Wnuk, Stanislaw F.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375949/
https://ncbi.nlm.nih.gov/pubmed/22711937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2012.04.050
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