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Structure of the Nucleotide Radical Formed during Reaction of CDP/TTP with the E441Q-α2β2 of E. coli Ribonucleotide Reductase
[Image: see text] The Escherichia coli ribonucleotide reductase (RNR) catalyzes the conversion of nucleoside diphosphates to deoxynucleotides and requires a diferric-tyrosyl radical cofactor for catalysis. RNR is composed of a 1:1 complex of two homodimeric subunits: α and β. Incubation of the E441Q...
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical Society
2008
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651750/ https://ncbi.nlm.nih.gov/pubmed/19128178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja806693s |
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