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The structural basis for substrate versatility of chloramphenicol acetyltransferase CAT(I)
Novel antibiotics are needed to overcome the challenge of continually evolving bacterial resistance. This has led to a renewed interest in mechanistic studies of once popular antibiotics like chloramphenicol (CAM). Chloramphenicol acetyltransferases (CATs) are enzymes that covalently modify CAM, ren...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3375752/ https://ncbi.nlm.nih.gov/pubmed/22294317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2036 |
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