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Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB

The emergence of multidrug-resistant and extensively drug-resistant (XDR) tuberculosis (TB) is a serious global threat. Aminoglycoside antibiotics are used as a last resort to treat XDR-TB. Resistance to the aminoglycoside kanamycin is a hallmark of XDR-TB. Here, we reveal the function and structure...

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Detalhes bibliográficos
Main Authors: Chen, Wenjing, Biswas, Tapan, Porter, Vanessa R., Tsodikov, Oleg V., Garneau-Tsodikova, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116390/
https://ncbi.nlm.nih.gov/pubmed/21628583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105379108
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