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Chemical and structural insights into the regioversatility of the aminoglycoside acetyltransferase Eis
A recently discovered cause of resistance of tuberculosis to a drug of last resort, the aminoglycoside kanamycin, is modification of this drug by the enhanced intracellular survival (Eis) protein. Eis is a structurally and functionally unique acetyltransferase with an unusual capability of acetylati...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947475/ https://ncbi.nlm.nih.gov/pubmed/24106131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300359 |
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