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Chemical and structural insights into the regioversatility of the aminoglycoside acetyltransferase Eis

A recently discovered cause of resistance of tuberculosis to a drug of last resort, the aminoglycoside kanamycin, is modification of this drug by the enhanced intracellular survival (Eis) protein. Eis is a structurally and functionally unique acetyltransferase with an unusual capability of acetylati...

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Bibliografske podrobnosti
Main Authors: Houghton, Jacob L., Biswas, Tapan, Chen, Wenjing, Tsodikov, Oleg V., Garneau-Tsodikova, Sylvie
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947475/
https://ncbi.nlm.nih.gov/pubmed/24106131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201300359
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