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Induced heterodimerization and purification of two target proteins by a synthetic coiled-coil tag

A synthetic de novo designed heterodimeric coiled-coil was used to copurify two target fluorescent proteins, Venus and enhanced cyan fluorescent protein (ECFP). The coiled-coil consists of two 21-amino acid repetitive sequences, (EIAALEK)(3) and (KIAALKE)(3), named E3 and K3, respectively. These seq...

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Autors principals: Fernandez-Rodriguez, Jesus, Marlovits, Thomas C
Format: Artigo
Idioma:Inglês
Publicat: Wiley Subscription Services, Inc., A Wiley Company 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375751/
https://ncbi.nlm.nih.gov/pubmed/22362668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2035
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