Development and Characterization of a Vaginal Film Containing Dapivirine, a Non- nucleoside Reverse Transcriptase Inhibitor (NNRTI), for prevention of HIV-1 sexual transmission

Dapivirine, a non-nucleoside reverse transcriptase inhibitor, is a potent and promising anti-HIV molecule. It is currently being investigated for use as a vaginal microbicide in two dosage forms, a semi-solid gel and a silicone elastomer ring. Quick-dissolving films are promising and attractive dosa...

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Main Authors: Akil, Ayman, Parniak, Michael A., Dezzuitti, Charlene S., Moncla, Bernard J., Cost, Marilyn R., Li, Mingguang, Rohan, Lisa Cencia
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375737/
https://ncbi.nlm.nih.gov/pubmed/22708075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-011-0022-6
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