Role of Phosphatidylinositol Clathrin Assembly Lymphoid-Myeloid Leukemia (PICALM) in Intracellular Amyloid Precursor Protein (APP) Processing and Amyloid Plaque Pathogenesis

One of the pathological hallmarks of Alzheimer disease is the accumulation of amyloid plaques in the extracellular space in the brain. Amyloid plaques are primarily composed of aggregated amyloid β peptide (Aβ), a proteolytic fragment of the transmembrane amyloid precursor protein (APP). For APP to...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Xiao, Qingli, Gil, So-Chon, Yan, Ping, Wang, Yan, Han, Sharon, Gonzales, Ernie, Perez, Ronaldo, Cirrito, John R., Lee, Jin-Moo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Neurobiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375549/
https://ncbi.nlm.nih.gov/pubmed/22539346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.338376
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares