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Regulation of T Cell Homeostasis and Responses by Pten

The generation of lipid products catalyzed by PI3K is critical for normal T cell homeostasis and a productive immune response. PI3K can be activated in response to antigen receptor, co-stimulatory, cytokine, and chemokine signals. Moreover, dysregulation of this pathway frequently occurs in T cell l...

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Detalhes bibliográficos
Main Authors: Newton, Ryan H., Turka, Laurence A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375464/
https://ncbi.nlm.nih.gov/pubmed/22715338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00151
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