Naïve T Cell Homeostasis Regulated by Stress Responses and TCR Signaling

The survival of naïve T cells is believed to require signals from TCR–pMHC interactions and cytokines such as IL-7. In contrast, signals that negatively impact naïve T cell survival are less understood. We conducted a forward genetic screening of mice and found a mutant mouse line with reduced numbe...

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Vydáno v:Front Immunol
Hlavní autoři: Kamimura, Daisuke, Atsumi, Toru, Stofkova, Andrea, Nishikawa, Naoki, Ohki, Takuto, Suzuki, Hironao, Katsunuma, Kokichi, Jiang, Jing-jing, Bando, Hidenori, Meng, Jie, Sabharwal, Lavannya, Ogura, Hideki, Hirano, Toshio, Arima, Yasunobu, Murakami, Masaaki
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681834/
https://ncbi.nlm.nih.gov/pubmed/26734005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00638
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