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Novel 3-Nitro-1H-1,2,4-triazole-based Amides and Sulfonamides as Potential anti-Trypanosomal Agents

A series of novel 3-nitro-1H-1,2,4-triazole-(and in some cases 2-nitro-1H-imidazole)-based amides and sulfonamides were characterized for their in vitro anti-trypanosomal and antileishmanial activities as well as mammalian toxicity. Out of 36 compounds tested, 29 (mostly 3-nitro-1H-1,2,4-triazoles)...

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Hlavní autoři: Papadopoulou, Maria V., Bloomer, William D., Rosenzweig, Howard S., Chatelain, Eric, Kaiser, Marcel, Wilkinson, Shane R., McKenzie, Caroline, Ioset, Jean-Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375360/
https://ncbi.nlm.nih.gov/pubmed/22550999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm300508n
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