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The Chemistry and Biology of Oligonucleotide Conjugates

Short DNA or RNA oligonucleotides have tremendous potential as therapeutic agents. Because of their ability to engage in Watson-Crick base pairing they can interact with messenger mRNA or pre-mRNA targets with high selectivity and thus offer the possibility of precise manipulation of gene expression...

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Detalhes bibliográficos
Main Authors: Juliano, R.L., Ming, Xin, Nakagawa, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374910/
https://ncbi.nlm.nih.gov/pubmed/22353142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar2002123
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