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Probing Minor Groove Hydrogen-bonding Interactions Between RB69 DNA Polymerase and DNA

Minor groove hydrogen bonding (HB) interactions between DNA polymerases and N3 of purines or O2 of pyrimidines have been proposed to be essential for DNA synthesis from results obtained using various nucleoside analogues lacking the N3 or O2 contacts that interfered with primer-extension. Since ther...

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Detalhes bibliográficos
Main Authors: Xia, Shuangluo, Christian, Thomas D., Wang, Jimin, Konigsberg, William H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374494/
https://ncbi.nlm.nih.gov/pubmed/22571765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300416z
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