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Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant
Recent structures of DNA polymerase complexes with dGMPCPP/dT and dCTP/dA mispairs at the insertion site have shown that they adopt Watson-Crick geometry in the presence of Mn(2+) indicating that the tautomeric or ionization state of the base has changed. To see whether the tautomeric or ionization...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Wiley-Blackwell
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3970900/ https://ncbi.nlm.nih.gov/pubmed/24458997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2434 |
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