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Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant

Recent structures of DNA polymerase complexes with dGMPCPP/dT and dCTP/dA mispairs at the insertion site have shown that they adopt Watson-Crick geometry in the presence of Mn(2+) indicating that the tautomeric or ionization state of the base has changed. To see whether the tautomeric or ionization...

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Détails bibliographiques
Auteurs principaux: Xia, Shuangluo, Konigsberg, William H
Format: Artigo
Langue:Inglês
Publié: Wiley-Blackwell 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970900/
https://ncbi.nlm.nih.gov/pubmed/24458997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2434
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