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Concise route to a series of novel 3-(tetrazol-5-yl)quinoxalin-2(1H)-ones

This report presents a novel three step solution phase protocol to synthesize 3-(tetrazol-5-yl)quinoxalin-2(1H)-ones. The strategy utilizes ethyl glyoxalate and mono-N-Boc-protected-o-phenylenediamine derivatives in the Ugi-Azide multi-component reaction (MCR) to generate a unique 1,5-disubstituted...

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Main Authors: Gunawan, Steven, Nichol, Gary, Hulme, Christopher
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374393/
https://ncbi.nlm.nih.gov/pubmed/22707799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2012.01.080
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