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p97 complexes as signal integration hubs

In the ubiquitin-proteasome system, a subset of ubiquitylated proteins requires the AAA+ ATPase p97 (also known as VCP or Cdc48) for extraction from membranes or protein complexes before delivery to the proteasome for degradation. Diverse ubiquitin adapters are known to link p97 to its client protei...

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Bibliografische gegevens
Hoofdauteur: Meyer, Hemmo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374291/
https://ncbi.nlm.nih.gov/pubmed/22694940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-10-48
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