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Distinct conformations of the protein complex p97-Ufd1-Npl4 revealed by electron cryomicroscopy
p97 is a key regulator of numerous cellular pathways and associates with ubiquitin-binding adaptors to remodel ubiquitin-modified substrate proteins. How adaptor binding to p97 is coordinated and how adaptors contribute to substrate remodeling is unclear. Here we present the 3D electron cryomicrosco...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268311/ https://ncbi.nlm.nih.gov/pubmed/22232657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114341109 |
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